U.S.-Mexico relations refer to the political, economic, and cultural interactions between the United States and Mexico. These two neighboring countries share a long and complex history characterized by periods of cooperation and conflict. Key issues in U.S.-Mexico relations include trade, immigration, security, and environmental cooperation. Both countries have strong economic ties, with Mexico being one of the United States' largest trading partners. Immigration is also a significant issue, with millions of Mexicans living in the United States and ongoing debates about border security and immigration policy. Overall, U.S.-Mexico relations have a significant impact on both countries and the broader region of North America.